From 653d4bfd6683bb11906e7f9f28d0ea6b69b08b6e Mon Sep 17 00:00:00 2001 From: "Cody, Jonathan William" Date: Mon, 15 May 2023 12:59:53 -0500 Subject: [PATCH] Update README.md --- README.md | 8 ++++---- 1 file changed, 4 insertions(+), 4 deletions(-) diff --git a/README.md b/README.md index 829be8f..c95654d 100644 --- a/README.md +++ b/README.md @@ -3,7 +3,7 @@ Jonathan W. Cody This repository contains all the code needed to replicate the following article. MATLAB R2018b or later is required. -Cody JW, Ellis-Connell AL, O’Connor SL, Pienaar E. "Mathematical modeling indicates that regulatory inhibition of CD8+ T cell cytotoxicity can limit efficacy of IL-15 immunotherapy in cases of high pre-treatment SIV viral load." +*Cody JW, Ellis-Connell AL, O’Connor SL, Pienaar E. "Mathematical modeling indicates that regulatory inhibition of CD8+ T cell cytotoxicity can limit efficacy of IL-15 immunotherapy in cases of high pre-treatment SIV viral load."* ========================= @@ -22,7 +22,7 @@ To replicate the article, unzip the entire repository into a folder and run the ========================= -The repository containts the following data (MATLAB .mat files): +**The repository containts the following data (MATLAB .mat files):** 'N803_DataSet_1.mat' (Cohort 1 calibration data) Source: Ellis-Connell AL, Balgeman AJ, Zarbock KR, Barry G, Weiler A, Egan JO, et al. "ALT-803 Transiently Reduces Simian Immunodeficiency Virus Replication in the Absence of Antiretroviral Treatment." Journal of virology. 2018;92(3). @@ -39,7 +39,7 @@ Source: Webb GM, Li S, Mwakalundwa G, Folkvord JM, Greene JM, Reed JS, et al. "T ========================= -In addition to the MATLAB scripts referenced above, this repository contains the following functions: +**In addition to the MATLAB scripts referenced above, this repository contains the following functions:** 'N803_model_2.m' (solves ODE model for N-803 treatment of SIV) @@ -65,7 +65,7 @@ In addition to the MATLAB scripts referenced above, this repository contains the 'N803_single_2.m' (calls 'N803_model_2.m', but first solves for ICs and parameters to start from one fixed point) -In 'Analyzer' folder: +**In 'Analyzer' folder:** 'calibrator.m' (called by 'main.m' scripts; calibrates model parameters via multi-start local-search)