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 # N-803_SIV_Model
-ODE model of viral and immune dynamics in response to treatment of SIV with IL-15 superagonist N-803
+Jonathan W. Cody
+
+This repository contains all the code needed to replicate the following journal article, soon to be submitted to PLoS Computational Biology. MATLAB R2018b or later is required.
+
+"Mathematical modeling indicates that regulatory inhibition of CD8+ T cell cytotoxicity can limit efficacy of IL-15 immunotherapy in cases of high pre-treatment SIV viral load"
+Article Authors: Jonathan W. Cody, Amy L. Ellis-Connell, Shelby L. O’Connor, Elsje Pienaar
+
+To replicate the article, unzip the entire repository into a folder and run the code in the following order:
+
+  1. "main_shared_calibration_2022_08_18.m"
+  2. "main_singles_calibration_2022_09_25.m"
+  3. "N803_collector_2.m"
+  4. "N803_plotter_2.m"
+  5. "N803_plotter_2_parameters.m"
+  
+The following is list of files (INCOMPLETE)
 
 'N803_model_1.m' = single-compartment model for article 1