Skip to content

Commit

Permalink
Update README.md
Browse files Browse the repository at this point in the history
  • Loading branch information
cody2 authored Jan 8, 2023
1 parent 306254e commit e76038f
Showing 1 changed file with 16 additions and 1 deletion.
17 changes: 16 additions & 1 deletion README.md
Original file line number Diff line number Diff line change
@@ -1,5 +1,20 @@
# N-803_SIV_Model
ODE model of viral and immune dynamics in response to treatment of SIV with IL-15 superagonist N-803
Jonathan W. Cody

This repository contains all the code needed to replicate the following journal article, soon to be submitted to PLoS Computational Biology. MATLAB R2018b or later is required.

"Mathematical modeling indicates that regulatory inhibition of CD8+ T cell cytotoxicity can limit efficacy of IL-15 immunotherapy in cases of high pre-treatment SIV viral load"
Article Authors: Jonathan W. Cody, Amy L. Ellis-Connell, Shelby L. O’Connor, Elsje Pienaar

To replicate the article, unzip the entire repository into a folder and run the code in the following order:

1. "main_shared_calibration_2022_08_18.m"
2. "main_singles_calibration_2022_09_25.m"
3. "N803_collector_2.m"
4. "N803_plotter_2.m"
5. "N803_plotter_2_parameters.m"

The following is list of files (INCOMPLETE)

'N803_model_1.m' = single-compartment model for article 1

Expand Down

0 comments on commit e76038f

Please sign in to comment.